Radiesse
Radiesse
Calcium Hydroxylapatite Injectable Biostimulator
Radiesse® Biostimulator
Radiesse® is an FDA-approved injectable implant made with calcium hydroxylapatite microspheres suspended in a gel carrier. Depending on the formulation and authorized treatment area, it may provide immediate structural support while also supporting gradual improvement in skin quality. At DermaPhi, treatment is carefully planned according to anatomy, tissue quality, goals, and the product’s specific FDA-approved indication.
Best For
Lower-Face Folds, Jawline, Hands & Décolleté
Treatment Style
Structural Support & Collagen Biostimulation
How Radiesse Works
Radiesse contains calcium hydroxylapatite, or CaHA, microspheres within a carboxymethylcellulose gel. The gel can create an early smoothing or contouring effect, while the CaHA material acts as a scaffold that supports the skin’s natural production of collagen and elastin over time. The product is gradually metabolized by the body.
Potential Treatment Benefits
Facial Wrinkle Correction
FDA approved for the correction of moderate to severe facial wrinkles and folds, including nasolabial folds.
Jawline Definition
Radiesse (+) is approved for improving moderate to severe loss of jawline contour in adults over 21.
Hand Rejuvenation
Radiesse is approved to correct volume loss in the back of the hands and reduce the visible prominence of veins and tendons.
Décolleté Renewal
When diluted 1:2 with sterile saline, Radiesse is approved for correction of décolleté wrinkles in adults aged 22 and older.
FDA-Approved Treatment Areas
Customized Radiesse Options
Radiesse and Radiesse (+) are used differently depending on the treatment goal, anatomical area, and approved indication.
Radiesse
Structure & Volume SupportUsed for approved facial folds and hand volume loss, with a CaHA-and-gel formulation that provides immediate support and gradual biostimulation.
Radiesse (+)
Lidocaine & Jawline ContourContains lidocaine and is approved for jawline contour improvement as well as moderate to severe facial wrinkles and folds.
1:2 Diluted Radiesse
Décolleté Wrinkle TreatmentA specific 1:2 dilution with sterile saline is FDA approved for correction of décolleté wrinkles in adults aged 22 and older.
Your Treatment Experience
Consultation
Your provider evaluates your anatomy, skin quality, allergies, medications, medical history, prior injectables, and treatment goals.
Customized Injection
The exact formulation, amount, depth, and placement technique are selected for the approved treatment area.
Aftercare & Follow-Up
You receive instructions for swelling, bruising, activity, skincare, and symptoms that require prompt medical evaluation.
Provider Experience Matters
Radiesse is a long-lasting injectable that must be placed with careful attention to anatomy and the approved treatment area. It is not managed with hyaluronidase in the way many hyaluronic-acid fillers can be.
Important Safety Information
Radiesse and Radiesse (+) should not be used in patients with severe allergies, a history of anaphylaxis or multiple severe allergies, known hypersensitivity to product components, or bleeding disorders. Radiesse (+) is also contraindicated in patients with hypersensitivity to lidocaine or amide-type anesthetics. Accidental injection into a blood vessel can cause embolization, vessel occlusion, tissue death, vision impairment or blindness, stroke, and other serious injury.
Frequently Asked Questions
Is Radiesse a filler or a biostimulator?
It is both. Radiesse is an FDA-approved dermal filler that provides immediate structural support and also acts as an injectable biostimulator through its calcium hydroxylapatite microspheres.
How long do Radiesse results last?
Duration varies by treatment area, amount, technique, metabolism, and individual response. FDA notes that calcium hydroxylapatite filler effects may last approximately 18 months, while product-specific clinical data vary by indication.
Can Radiesse be dissolved?
No. Radiesse is not dissolved with hyaluronidase. This makes careful product selection, placement, and provider training especially important.
What downtime should I expect?
Temporary redness, swelling, pain, tenderness, bruising, itching, lumps, or firmness may occur. Recovery varies by area, volume, and technique.
Can Radiesse be used around the eyes or in the lips?
The manufacturer states that safety and effectiveness have not been established for the lips or the area around the eyes. Treatment should remain within approved indications unless a qualified provider clearly explains an off-label use and its risks.
What is hyperdiluted Radiesse?
The term commonly describes Radiesse mixed with a larger amount of diluent to spread the product over a broader area. In the United States, a specific 1:2 dilution with sterile saline is FDA approved for décolleté wrinkle correction; other dilutions or areas may be off label.
Will Radiesse show on imaging?
Calcium hydroxylapatite microspheres can be visible on X-rays and CT scans. Tell your physician and radiologist that you have received Radiesse, particularly when imaging the treated area.
Is Radiesse appropriate during pregnancy or breastfeeding?
The safety and effectiveness of Radiesse during pregnancy and breastfeeding have not been established. Discuss timing and alternatives with your healthcare provider.
Is Radiesse right for everyone?
No. Active infection, severe allergies, bleeding disorders, allergy to product components, lidocaine sensitivity for Radiesse (+), medications, prior filler complications, and other medical factors may affect eligibility.
Radiesse® and Radiesse® (+) are prescription injectable implants that should be administered only by qualified licensed professionals trained in facial and hand anatomy and the product’s approved indications. Potential risks include pain, swelling, bruising, redness, itching, infection, nodules, granulomas, asymmetry, migration, vascular occlusion, tissue necrosis, vision loss, blindness, stroke, and an unsatisfactory result. Radiesse (+) contains lidocaine. Product selection, dilution, placement, and treatment area must follow applicable labeling and professional standards. Individual results vary.
